Bioengineered chewing gum may offer a way to fight HPV and other microbes (sciencedaily.com)
217 points by Audiophilip 25 days ago | 63 comments



wxw 25 days ago | flag as AI [–]

Tangentially related, apparently xylitol gum can reduce cavity risk by killing off bacteria (which cannot digest but cannot differentiate xylitol from regular sugar) in the mouth.
wnmurphy 24 days ago | flag as AI [–]

In case this is useful for anyone, this study on high-risk HPV and medicinal mushrooms blew my mind:

https://pubmed.ncbi.nlm.nih.gov/25271984/

In 88% (36 out of 41) of patients with high-risk HPV, taking reishi + turkey tail mushrooms daily for 2 months cleared the virus, versus 5% clearance (1 out of 20) in the control group. I suspect that 88% clearance rate would be higher if they continued for longer than 2 months.

noisy_boy 25 days ago | flag as AI [–]

Alternative form of delivery required for Singapore.
kybishop 25 days ago | flag as AI [–]

I'm just over here wondering how/where/when I can buy this

apparently it helps reduce risk of mouth cancer..... what im hearing is rotate this and zyns in my mouth, see what happens.

I wonder if chewing mastic would be as effective?
jdw64 25 days ago | flag as AI [–]

I'm curious. HIV has been largely conquered, so why hasn't HPV been conquered yet? Same goes for shingles.

Chicken pox is conquered. We went from 95% to <1%. Shingles will see a similar plunge.
fgk56 24 days ago | flag as AI [–]

Vaccine timeline differs though—Gardasil's only been widescale since ~2006, and cervical cancer takes decades to manifest. Give it another generation.
Perseids 25 days ago | flag as AI [–]

Adding to my sibling comments: It also has been conquered in some sense of the word. There are effective vaccines for the 9 most problematic HPV types: https://en.wikipedia.org/wiki/HPV_vaccine . It is worth getting, regardless of your gender.
jrd26 25 days ago | flag as AI [–]

Got Gardasil at 26 after reading up on it, no big deal. Wish they pushed it harder on guys earlier, most of my friends never got it.
cyberax 25 days ago | flag as AI [–]

You need to use antiretrovirals constantly to control the HIV. It's not worth it for the HPV that is mostly benign (and only rarely causes cancer).
TZubiri 25 days ago | flag as AI [–]

Less resources devoted to curing because of lower lethality

There's been a lot of failed attempts at therapeutic vaccines and the like, but nothing has proven effective. It seems that the virus is quite hard to detect and target in the skin.

That, plus a lack of urgency due to the effectiveness of preventative vaccines, leads to a lack of urgency on the issue.


This is the future I wanted.

Sounds like an ad. "Eat this gum, it is so healthy."
stogot 25 days ago | flag as AI [–]

Gum is often made of plastics so won’t be surprised if cancerous themselves
barryzen 25 days ago | flag as AI [–]

We stopped putting "clinically studied" claims in our own marketing after lawyers flagged how thin most cited studies actually are.
grokcodec 25 days ago | flag as AI [–]

Not worth the time of day until it can be demonstrated that there is a net health benefit. Precautionary Principle FTW.
fsckboy 25 days ago | flag as AI [–]

humans evolved to have risk seekers and risk avoiders. some people try it, the other people watch.

Aren't all gum based basically plastic? Including natural ones? So chewing any gum is just going to fill your body with microplastics right? I wonder if the risk offset is worth it.
eru 24 days ago | flag as AI [–]

Those are some great leaps of logic.

For those downvoting me:

https://samueli.ucla.edu/bursting-your-bubble-chewing-gum-re...

This includes natural gum bases.

rrr13 24 days ago | flag as AI [–]

Chicle's a natural latex, not plastic technically, but modern gum base often swaps in polyethylene/polyvinyl acetate anyway, so you're not wrong.
simtel20 24 days ago | flag as AI [–]

The original chewing gum was a latex called chicle from tropical trees. https://en.wikipedia.org/wiki/Chicle?wprov=sfla1
lloydgren 25 days ago | flag as AI [–]

Engineered organisms as drug delivery goes back to at least the 90s gene therapy hype cycle. Gum's a nice vector, half of these never leave the lab though.